3 Discovering mutations

In this module, we’ll use DNA sequencing data from human families to explore the relationship between parental age and de novo mutations in their children.

3.0.0.1 Learning objectives

After completing this chapter, you’ll be able to:

  1. Create plots to visualize the relationship between two variables.
  2. Interpret the results of a linear model.
  3. Compare the impact of maternal vs. paternal age on de novo mutation counts.
  4. Explain what a confidence interval is and why it’s useful.