9 Scans for selection

In this lab, we’ll explore three methods for identifying signatures of selection: F_ST, population branch statistic (PBS), and extended haplotype homozygosity (EHH).

9.0.0.1 Learning objectives

After completing this chapter, you’ll be able to:

1. Describe the genetic signatures of selection and what they reveal about the strength and timing of the selective sweep.
2. Calculate and interpret population differentiation with F_ST.
3. Understand why PBS provides additional information over two-population tests of selection.
4. Explain how EHH and iHS leverage haplotype information to identify selection.

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