9.22 Integrated haplotype statistic

If you calculate EHH for both the new and ancestral haplotypes at a locus, you can compare them to calculate the integrated haplotype statistic (iHS), which is the ratio of the area under the EHH curve for the derived and ancestral haplotypes.

Fig. 12. Comparing the EHH of haplotypes carrying the derived and ancestral alleles to calculate iHS.
Fig. 12. Comparing the EHH of haplotypes carrying the derived and ancestral alleles to calculate iHS.
All illustrations CC-BY.
All other materials CC-BY unless noted otherwise.