11 Gene expression

In this lab, we’ll use data from the Genotype-Tissue Expression (GTEx) Project to explore how genetic variation impacts gene expression.

11.0.0.1 Learning objectives

After completing this chapter, you’ll be able to:

  1. Define expression and splicing quantitative trait loci.
  2. Explain the challenge of multiple testing in eQTL studies and how it is typically handled.
  3. Navigate the GTEx Portal to find expression data for genes of interest.